MBE: AINE IM vs VO

La pregunta

La via intramuscular és millor que la via oral a l'hora de tractar un dolor agut?

Com formular la pregunta

• P-> Problema: dolor agut
• I-> Intervenció: AINE VO
• C-> Control: AINE IM
• O-> Output (Resultat): millora del dolor subjectiva (EVA)

Cerca

TripDatabase

TripDatabase en Español

dolor AINE intramuscular oral

 En cuanto a la vía de administración de los AINE, la revisión Cochrane [1] sugiere que
 no hay evidencia para recomendar otra vía que no sea la oral en la lumbalgia aguda.

TripDatabase

pain NSAID intramuscular oral

 Avoid intramuscular (IM) administration in older adults. 
 Because of muscle wasting and less fatty tissue in older as compared to younger adults, 
 intramuscular absorption of analgesics in older adults is slowed 
 and may result in delayed/prolonged effect of IM injections, 
 altered analgesic serum levels and possible toxicity with repeated injections [2]. 
 

Conner & Deane, 1995; Egbert et al., 1990; Erstad et al., 1997; Pasero, Portenoy, & McCaffery, 1999; VHA/DoD, 2002). Evidence Grade = B

Bibliografia

1. van Tulder MW, Scholten RJ, Koes BW, and Deyo RA. Non-steroidal anti-inflammatory drugs for low back pain. Cochrane Database Syst Rev. 2000(2):CD000396. DOI:10.1002/14651858.CD000396 |
2. Austin KL, Stapleton JV, and Mather LE. Multiple intramuscular injections: a major source of variability in analgesic response to meperidine. Pain. 1980 Feb;8(1):47-62. DOI:10.1016/0304-3959(80)90089-5 |